AIM Honor (Ningbo) Biopharmaceutical Co., Ltd. is a manufacturer and supplier of Freeze-Dried Rabies Vaccine Vero Cell for Human Use. We support bulk purchasing and cross-border supply of products to provide safe and effective vaccine products to customers worldwide.
A rabies vaccine is a biological product used to prevent rabies virus infection. It stimulates the body to produce specific antibodies that neutralize the invading rabies virus, reducing the risk of illness (the fatality rate of rabies is almost 100%, and vaccination is the key preventive measure).
The rabies vaccine was invented by the French scientist Louis Pasteur in 1885. It was first used on Joseph Meister, a 9-year-old boy bitten by a rabid dog, successfully saving the lucky child's life—this is the earliest recorded use of the rabies vaccine in human history.
In the mid-20th century, inactivated rabies vaccines were developed, addressing the safety issues of attenuated live vaccines and becoming the mainstream for human use.
In the 1980s, with the rise of genetic engineering technology, recombinant rabies vaccines entered the research and development phase, and were gradually marketed in the 1990s, further improving safety and immunogenicity.
To date, inactivated vaccines remain the global mainstream for human use, while genetically engineered vaccines are rapidly gaining popularity due to their advantages. The "five-dose schedule" and "2-1-1 schedule" have become standardized vaccination procedures for post-exposure prophylaxis.
Inactivated Vaccine: The mainstream type, made from inactivated rabies virus strains. It features high safety and stable immunogenicity, suitable for both humans and animals.
Attenuated Live Vaccine: Produced by weakening the virulence of the rabies virus. It has strong immunogenicity but slightly lower safety than inactivated vaccines, and is mostly used for animal immunization (rarely for human use in some regions).
Genetically Engineered Vaccine: Expresses viral antigens (such as glycoprotein G) through genetic recombination technology. It has high purity, mild side effects, and is a development direction in recent years (e.g., CHO cell-expressed vaccines).
| Vaccine Type | Core Components | Common Packaging Specifications | Core Features | Application Scenarios |
| Inactivated Vaccine (Human) | Inactivated rabies virus (e.g., PV strain, CTN-1V strain) | 1ml/vial (single dose), 2ml/vial (double dose) | High safety, long antibody duration (≥1 year) | Pre-exposure/post-exposure prophylaxis for humans (mainstream choice) |
| Genetically Engineered Vaccine | Recombinant rabies virus glycoprotein (G protein) | 0.5ml/vial, 1ml/vial | High purity, mild side effects, short production cycle | Pre-exposure/post-exposure prophylaxis for humans (new preferred option) |
| Attenuated Live Vaccine (Veterinary) | Attenuated rabies virus (e.g., SAD strain) | 5ml/bottle, 10ml/bottle | Strong immunogenicity, low cost | Mass immunization of animals such as dogs and cats |
Is it still useful to get vaccinated more than 24 hours after being bitten by a dog?
Yes! As long as no symptoms occur, get vaccinated as soon as possible. For severe exposure, rabies immunoglobulin (RIG) should be injected simultaneously—do not give up vaccination due to delayed timing.
Is it normal to experience redness, swelling, or low-grade fever after vaccination?
These are normal local/systemic reactions (incidence rate: approximately 10%-20%), which usually subside on their own within 1-2 days without special treatment. Seek medical attention immediately for high fever or allergies.
Can pregnant or lactating women be vaccinated?
Yes! Rabies vaccines (inactivated or genetically engineered) have no adverse effects on fetuses or infants. Prioritize vaccination in case of exposure.
Can rabies occur after completing the vaccination?
It is extremely rare (e.g., virus latency before vaccination, severe exposure without RIG). The protection rate exceeds 99% after standardized vaccination.
If a pet has been vaccinated, do I still need to get vaccinated if scratched by it?
Yes! The protection rate of animal vaccines is not 100%, and virus carriage cannot be completely ruled out. Follow the post-exposure vaccination procedure.
If you have any further needs or inquiries, please feel free to contact us via international@aimbio.com