AIM Honor (Ningbo) Biopharmaceutical Co., Ltd. is a professional supplier specializing in the research, development, and manufacturing of dog bite vaccines. We offer rabies vaccines, covering both conventional Vero cell rabies vaccines and next-generation serum-free Vero cell rabies vaccines, specifically designed for Category II/III exposures such as dog bites and scratches.
Manufactured by AIM Honor, our dog bite vaccine utilizes local aG virus strains and advanced serum-free culture
technology. It boasts a 100% antibody seroconversion rate within 14 days, is administered via intramuscular
injection only, and contains no preservatives or bovine serum. With superior safety and immunogenicity, stable
supply, and support for bulk purchasing, it is a core choice for rabies prevention and control after dog exposure!
Product Features
This Dog Bite Vaccine is a targeted rabies preventive product for post-exposure scenarios caused by dog-related
injuries, with National Drug Approval Number S20073014 for the conventional version and the serum-free version
entering the marketing approval stage.
The conventional vaccine is prepared by inoculating rabies fixed virus aG strain on Vero cells, while the serum-free
vaccine innovatively adopts serum-free Vero cell culture technology, eliminating the addition of bovine serum
throughout the entire production process (including cell revival, expansion, and virus cultivation), which
fundamentally avoids the risks of viral contamination, batch-to-batch quality variability, and allergic reactions
caused by bovine serum.
In line with WHO rabies exposure classification standards, the vaccine is suitable for Category II (non-bleeding
bites/scratches) and Category III (bleeding bites/scratches, mucosal contact) dog-related exposures. After
intramuscular injection (1.0ml per dose, administered on days 0, 3, 7, 14, and 28), it can rapidly stimulate the
body to produce high-titer neutralizing antibodies, with 100% seroconversion rate at 14 days, far exceeding the WHO
effective protection standard of 0.5 IU/ml. For Category III exposures, it can be used in combination with rabies
immunoglobulin (20IU/kg) to form a comprehensive protective barrier.
Product Specification
Item
Conventional Vero Cell Version
Serum-free Vero Cell Version
Manufacturer
AIM Honor (Ningbo) Biopharmaceutical Co., Ltd.
AIM Honor (Ningbo) Biopharmaceutical Co., Ltd.
Active Ingredient
Inactivated rabies fixed virus aG strain
Inactivated rabies fixed virus PV-2061 strain
Dosage Form
Freeze-dried
Freeze-dried
Specification
1.0ml per vial after reconstitution
1.0ml per vial after reconstitution
Human Dose
1.0ml per dose, intramuscular injection
1.0ml per dose, intramuscular injection
Potency Standard
≥2.5 IU/dose, actual detection mean ≈6.0 IU/dose
≥2.5 IU/dose, post-immunization antibody GMC significantly higher than protection threshold
Key Process
Conventional Vero cell culture, no preservatives
Serum-free culture throughout, no bovine serum residue
Immunization Schedule
1 dose each on days 0, 3, 7, 14, 28 post-exposure (5-dose schedule)
Supports 5-dose schedule and WHO simplified 4-dose schedule, immune persistence over 3 months
Storage Condition
Store at 2-8℃ away from light, freezing strictly prohibited
Store at 2-8℃ away from light, freezing strictly prohibited
Shelf Life
36 months
36 months
Core Advantages
Dual-category to meet needs: Conventional version has mature technology and high
cost-effectiveness, with cumulative supply exceeding 100 million doses; serum-free version is an upgraded product,
avoiding bovine serum-related risks, with adverse reactions mainly mild Grade 1-2, no Grade 4 or above severe
reactions, and better safety.
High-efficiency immune guarantee: 100% antibody seroconversion rate in 14 days; antibody GMC of
serum-free version in both 5-dose and 4-dose groups far exceeds protection standards, and immune persistence can
reach more than 3 months, providing long-term protection for dog bite-exposed populations.
Strong compliance: Conventional version Dog Bite Vaccine complies with national pharmacopoeia
standards; serum-free version has completed Phase III clinical trials and CDE has accepted the marketing
application; both support sequential vaccination with other brands of vaccines, suitable for global dog bite-related
rabies prevention and control scenarios.
Application Scenarios
Medical institutions: Community hospitals and emergency centers for emergency post-exposure
vaccination after dog bites; can be combined with rabies immunoglobulin to provide comprehensive protection for
Category III exposure patients.
Pet-related scenarios: Pet hospitals and pet markets provide post-exposure prevention for dog
breeders and pet practitioners, reducing occupational exposure risks.
Public health prevention and control: Suitable for bulk procurement in high-incidence areas of
dog-transmitted rabies such as Asia and Africa, supporting large-scale immunization work.
Hot Tags: Dog Bite Vaccine, China, Manufacturer, Supplier, Factory
For inquiries about human rabies vaccine, hepatitis B vaccine, hepatitis A vaccine or price list, please leave your email to us and we will be in touch within 24 hours.
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